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Sequence Analysis of the Nucleocapsid Protein Gene of Rat Coronavirus SDAV-681

Identifieur interne : 001337 ( Main/Exploration ); précédent : 001336; suivant : 001338

Sequence Analysis of the Nucleocapsid Protein Gene of Rat Coronavirus SDAV-681

Auteurs : Satoshi Kunita [Japon] ; Miki Mori [Japon] ; Eiji Terada [Japon]

Source :

RBID : ISTEX:712B97E9FDA0BB4FBAA9661E8B50CA7B9DBE66B6

Abstract

Abstract: The nucleotide sequence of the 3′-end of the genomic RNA of sialodacryoadenitis virus strain 681 (SDAV-681) was determined. A large open reading frame encoding a 454-amino-acid protein was identified as the nucleocapsid protein (N) gene, since the predicted protein is similar in size, chemical properties, and amino acid sequence to the N proteins of other coronaviruses. The amino acid variance of the N proteins between SDAV and mouse hepatitis virus (MHV) is not markedly different from that among MHV strains. A high degree of genetic relatedness between SDAV and MHV was revealed in the intergenic and 3′-noncoding sequences as well as in the N gene.

Url:
DOI: 10.1006/viro.1993.1158


Affiliations:


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<div type="abstract" xml:lang="en">Abstract: The nucleotide sequence of the 3′-end of the genomic RNA of sialodacryoadenitis virus strain 681 (SDAV-681) was determined. A large open reading frame encoding a 454-amino-acid protein was identified as the nucleocapsid protein (N) gene, since the predicted protein is similar in size, chemical properties, and amino acid sequence to the N proteins of other coronaviruses. The amino acid variance of the N proteins between SDAV and mouse hepatitis virus (MHV) is not markedly different from that among MHV strains. A high degree of genetic relatedness between SDAV and MHV was revealed in the intergenic and 3′-noncoding sequences as well as in the N gene.</div>
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{{Explor lien
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   |clé=     ISTEX:712B97E9FDA0BB4FBAA9661E8B50CA7B9DBE66B6
   |texte=   Sequence Analysis of the Nucleocapsid Protein Gene of Rat Coronavirus SDAV-681
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